It is widely known that cannabis has many medicinal benefits, with managing chronic pain, epilepsy, anxiety and treating the symptoms of PTSD among many more.
However, in the case of cannabinoids, a group of substances found in the cannabis plant, there is a risk that combining it with other prescription drugs could pose harmful drug-drug interactions, suggested new research undertaken by scientists at Washington State University (WSU).
The researchers looked at cannabinoids and their major metabolites found in cannabis users’ blood and found that they interfere with two families of enzymes that help metabolize a wide range of drugs prescribed for a variety of conditions. As a result, either the drugs’ positive effects might decrease or their negative effects might increase with too much building up in the body, causing unintended side effects such as toxicity or accidental overdose.
The findings examined the interaction between three of the most abundant cannabinoids – tetrahydrocannabinol (THC), cannabidiol (CBD), and cannabinol (CBN).
While more research …